Symptomatic therapy of pain syndrome, incl. with inflammatory processes of various origins
Tradename: Bi-Ketozhesik
Bi-Ketogesic
* Composition: Each tablet contains:
Ketoprofen 150 mg
* Auxiliary components:
Lactose monohydrate, microcrystalline cellulose, starch, magnesium stearate, croscarmellose sodium.
* Properties: NSAIDs. It has anti-inflammatory, analgesic and antipyretic effects. Ketoprofen blocks the action of the enzyme COX-1 and COX-2 and, in part, lipoxygenase, which leads to suppression of the synthesis of prostaglandins (including in the central nervous system, most likely in the hypothalamus).
Stabilizes in vitro and in vivo liposomal membranes, at high concentrations in vitro inhibits the synthesis of bradykinin and leukotrienes. Ketoprofen does not adversely affect the condition of the articular cartilage.
* Indications: Symptomatic therapy of pain syndrome, incl. with inflammatory processes of various origins.
* Method of administration and dosage: Inside, during or after meals, 1 tablet (150 mg) 1 time per day.
During a migraine, you can take 300 mg per day in divided doses.
The minimum effective dose should be used in the smallest possible course.
* Contraindications: Erosive and ulcerative lesions of the gastrointestinal tract in the acute phase, «aspirin triad», severe liver and / or kidney dysfunctions. III trimester of pregnancy. age up to 15 years.
Hypersensitivity to ketoprofen and salicylates.
* Precautionary measures: Ketoprofen can be taken with milk or taken with antacids to reduce the incidence of gastrointestinal distress. Antacids and milk do not affect the absorption of the drug.
During treatment, it is necessary to control the picture of peripheral blood and the functional state of the liver and kidneys, especially in elderly patients.
* Side effects: From the digestive system: pain in the epigastric region, nausea, vomiting, constipation or diarrhea, anorexia, gastralgia, abnormal liver function, rarely — erosive and ulcerative lesions of the gastrointestinal tract, bleeding and perforation of the gastrointestinal tract.
From the side of the central nervous system: headache, dizziness, tinnitus, drowsiness.
From the urinary system: renal dysfunction.
Allergic reactions: skin rash, rarely bronchospasm.
* Storage method: Store at a temperature not exceeding 30 degrees.
* Package: The cardboard box contains 3 blisters of 10 tablets and paper instructions.
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