Erec - 100 mg 12 Tablets

Treatment of erectile dysfunction characterized by the inability to achieve or maintain an erection of the penis sufficient for satisfactory intercourse.

Pulmonary hypertension.

Tradename: Erek

Erec

* Compound: Each tablet contains:

Sildenafil 100 mg.

* Auxiliary components: lactose monohydrate (milk sugar), microcrystalline cellulose, croscarmellose sodium, povidone K25, magnesium stearate.

* Properties: Selective inhibitor of cycloguanosine monophosphate (cGMP) -specific PDE5. PDE5, responsible for the breakdown of cGMP, is contained not only in the cavernous body of the penis, but also in the vessels of the lungs.

Restores impaired erectile function and provides a natural response to sexual arousal. Sildenafil does not have a direct relaxing effect on the corpora cavernosa, but actively enhances the relaxing effect of nitric oxide on this tissue. With sexual arousal, the local release of NO under the influence of sildenafil leads to inhibition of PDE5 and an increase the level of cGMP in the corpus cavernosum, resulting in relaxation of smooth muscles and increased blood flow in the corpus cavernosum.

As a PDE5 inhibitor, sildenafil increases the content of cGMP in the smooth muscle cells of the pulmonary vessels and causes them to relax. In patients with pulmonary hypertension, taking sildenafil leads to vasodilation of the lungs and, to a lesser extent, other vessels.

* Indications: Treatment of erectile dysfunction characterized by the inability to achieve or maintain an erection of the penis sufficient for satisfactory intercourse.

* Pulmonary hypertension.

Method of administration and dosage: Treatment of erectile dysfunction: taken orally approximately 1 hour before the planned sexual activity. A single dose is 50 mg. Taking into account the efficacy and tolerability, the dose can be increased to 100 mg or reduced to 25 mg. The maximum single dose is 100 m

The maximum frequency of use is 1 time /

For elderly patients over the age of 65 and

with concomitant renal or hepatic impairment, the dose is 25 mg.

Pulmonary hypertension: by mouth 20 mg 3 times / day with an interval of about 6-8 hours, regardless of food intake. The maximum daily dose is 60 mg. Patients with impaired renal function do not need dose adjustment, however, with poor tolerance, the dose is reduced to 20 mg 2 times / day.

* Contraindications: Simultaneous intake of nitric oxide or nitrate donors in any form, hypersensitivity to sildenafil.

* Precautions: Before starting to take sildenafil for the treatment of erectile dysfunction, a cardiovascular examination should be performed.

It should be used with caution in patients with anatomical deformity of the penis (for example, angulation, cavernous fibrosis or Peyronie’s disease) and people with diseases that predispose to the development of priapism (such as sickle cell anemia, multiple myeloma, or leukemia).

Should not be used in patients for whom sexual activity is undesirable.

Use with caution in patients with a tendency to bleeding, with gastric ulcer and duodenal ulcer in the acute phase, with hereditary retinitis pigmentosa.

Sildenafil is not used in patients under the age of 18.

* Side effects: From the side of the central nervous system: headache, hot flashes, dizziness, insomnia are possible.

From the digestive system: possible dyspepsia, asthenia, diarrhea, abdominal pain, nausea.

From the musculoskeletal system: arthralgia, myalgia, increased muscle tone.

From the respiratory system: nasal congestion,

pharyngitis, rhinitis, sinusitis, respiratory tract infections, respiratory failure.

From the side of the organ of vision: changes in vision (mild and transient; mainly a change in the color of objects, as well as increased perception of light and impaired vision), conjunctivitis.

* Storage method: At a temperature not higher than 30 C.

* Packaging: The cardboard box contains 3 blisters of 4 tablets, paper instructions.