Magnesium Plus - 30 Tablets

Adjuvant therapy during diuretic treatment and in severe burns.

Treatment of hypomagnesemia.

For muscle cramps as a result of magnesium depletion.

As a laxative for the treatment of constipation or as a bowel preparation prior to surgery or radiological, proctoscopic and sigmoidoscopic procedures.

For the treatment of dyspepsia and heartburn.

Trade name: Magnesium Plus

Composition: Each tablet contains:

Magnesium oxide — 400mg

Magnesium gluconate — 100mg

Properties: Magnesium is the second most abundant intracellular cation. It is a cofactor in more than 300 enzymatic reactions, including proteins of energy metabolism and nucleic acid products. Oral magnesium salt formulations are used as a supplement in patients with magnesium deficiency due to a restricted diet, alcoholism or magnesium depletion caused by drugs that break down magnesium (such as diuretics), or severe burns and regular exercise that increase magnesium production with sweat. Magnesium oxide can also be used as an antacid or laxative. The antacid mechanism of magnesium oxide involves reaction with water. In the presence of water, magnesium oxide is converted to magnesium hydroxide, which quickly reacts with stomach acid to form sa and magnesium chloride, thereby increasin gastric pH.

Indications: Adjuvant therapy during diuretic treatment and in severe burns. Treatment of hypomagnesemia. For muscle cramps as a result of magnesium depletion. As a laxative for the treatment of constipation or as a bowel preparation prior to surgery or radiological, proctoscopic and sigmoidoscopic procedures. For the treatment of dyspepsia and heartburn.

Mode of application: For the treatment of hypomagnesemia, adjuvant therapy and symptoms caused by magnesium depletion, 1-2 tablets per day, tolerated without diarrhea. For laxative effect or bowel preparation for research: 1 tablet at bedtime with a full glass of water. For the treatment of dyspepsia: 1 to 2 tablets per day.

Contraindications: With caution in patients with renal insufficiency. When used as laxatives, oral magnesium salts should be avoided in patients with gastric or intestinal obstruction. Use oral magnesium salts with caution in dehydrate patients. Repeated administration of oral magnesium salts can lead to severe dehydration due to fluid loss through the gastrointestinal tract.

Precautions: Take any other medicines and magnesium oxide at least 2 hours apart. Do not take magnesium as an antacid for more than 2 weeks unless directed by your doctor. Do not take magnesium oxide as a laxative for more than 1 week unless directed by your doctor.

Side effects: The most common reaction with oral magnesium salts is diarrhea.

Drug interaction: the simultaneous use of cardiac glycosides with magnesium salts can inhibit absorption and, possibly, reduce the concentration of cardiac glycosides in plasma. Diuretics can affect the concentration of magnesium in the kidneys. Concomitant use of laxatives can lead to magnesium toxicity, especially in patients with renal insufficiency. Administration of oral magnesium salts with oral tetracyclines or quinolone antibiotics may involve magnesium supplementation with other antacids containing magnesium, or fo absorbable complexes, which leads to decreased absorption of tetracyclines and non-quinolones. Do not give magnesium salts by mouth within 1 to 3 hours after taking oral tetracycline or oral fluoroquinolone.

Pregnancy and lactation: Do not use during pregnancy without consulting a doctor. Magnesium crosses the placenta and is excreted in breast milk.

Storage: Store at a temperature not exceeding 30C in a dry place out of the reach of children.

Packaging: The box contains 30 tablets and paper instructions.