Phenadone - Syrup125 ml

It is indicated for a large number of diseases amenable to glucocorticoid therapy, as well as as an adjunct for the treatment of cerebral edema.

Insect bites. Food allergies. Itchy skin rashes. Relieves itching, redness, swelling and irritation. Itchy rash with chickenpox.

Tradename: phenadon

Phenadone

Composition: Each 5 ml of syrup contains:

Dexamethasone 0.5 mg

Chlorpheniramine maleate 2 mg

Auxiliary components:

Methyl paraben, propyl paraben, glycerin, ethyl alcohol 95%, sugar.

Properties: Dexamethasone is a synthetic adrenal cortex hormone (corticosteroid) with glucocorticoid activity. It has anti-inflammatory and immunosuppressive effects, and also affects energy metabolism, glucose homeostasis and (through a negative feedback effect) the secretion of hypothalamic releasing hormone and trophic hormone of the adenohypophy

Chlorpheniramine maleate

Chlorphenamine is a blocker of HI-histamine receptors. Narrows the vessels of the nose, eliminates swelling and hyperemia of the mucous membrane of the nasal cavity, nasopharynx and paranasal sinuses; reduces exudative manifestations, suppresses the symptoms of allergic rhinitis.

Indications: It is indicated for a large number of diseases amenable to glucocorticoid therapy, as well as an adjunct for cerebral edema.

Insect bites. Food allergies. Itchy rashes. Relieves itching, redness, swelling and irritation. Itchy rash with chickenpox. Method of administration and dosage: Adults:

1 teaspoon per day.

Children:

0.01-0.1 mg / kg 1 time per day.

Contraindications: Hypersensitivity to the active substance or other ingredients of the drug.

Acute viral, bacterial and systemic fungal infections (without appropriate treatment).

Cushing’s Syndrome.

Vaccination with a live vaccine.

Breastfeeding period (except in emergencies).

Precautions: Patients undergoing long-term dexamethasone treatment may experience corticosteroid withdrawal (also without noticeable signs of adrenal insufficiency) a stopping therapy (fever, nasal discharge, conjunctival redness, headache, dizziness, drowsiness or irritability, muscle and joint pain, vomiting , weight loss, weakness, and frequent seizures). Therefore, the dose of dexamethasone should be gradually reduced.

Side effects: - decreased glucose tolerance, «steroid» diabetes mellitus or manifestation of latent diabetes mellitus.

— Itsenko-Cushing’s syndrome, weight gain.

-nicot, nausea, vomiting, increased or decreased appetite, flatulence, increased activity of «liver» transaminases and alkaline phosphatase, pancreatitis.

«-steroid» ulcer of the stomach and duodenum, erosive esophagitis, bleeding and perforation of the gastrointestinal tract.

- arrhythmias, bradycardia (up to cardiac arrest), development (in predisposed patients or increased severity of chronic heart failur increased blood pressure.

hypercoagulation, thrombosis.

delirium, disorientation, euphoria, hallucinations, manic-depressive psychosis, depression, paranoia. - increased intracranial pressure, nervousness, anxiety, insomnia, headache, dizziness, convulsions, vertigo.

pseudotumor of the cerebellum. sudden loss of vision (with parenteral administration, the deposition of crystals of the drug in the vessels of the eye is possible), posterior subcapsular cataract, increased intraocular pressure with possible damage to the optic nerve, trophic changes in the cornea, exophthalmos, the development of secondary bacterial, fungal or viral eye infections. negative nitrogen balance (increased protein breakdown), hyperlipoproteinemia. - increased sweating.

fluid and sodium retention (peripheral edema), hypokalemic syndrome (hypokalemia, arrhythmia, myalgia or muscle spasm, unusual weakness and fatigue). - deceleration of growth and ossification processes in children (premature closure of the epiphyseal growth zones).

- increased excretion of calcium, osteoporosis, pathological bone fractures, aseptic necrosis of the head of the humerus and femur, tendon rupture.

«-steroid» myopathy, muscle atrophy.

delayed wound healing, a tendency to develop pyoderma and candidiasis. - petechiae, ecchymosis, thinning of the skin, hyper- or hypopigmentation, steroid acne, striae.

generalized and local allergic reactions. - decreased immunity, development or exacerbation of infections.

- leukocyturia.

violation of the secretion of sex hormones (menstrual irregularities, hirsutism, impotence, delayed sexual development in children). withdrawal syndrome

Storage method: At a temperature not higher than 30 degrees.

Packaging: The cardboard box holds a 100 ml or 125 ml bottle.