Elimination of symptoms associated with seasonal allergic rhinitis (SAR) or urticaria for adults and children over 12 years of age.
Tradename: Telfast
Telfast
Structure: Each film-coated tablet contains 180 mg of Fexofenadine hydrochloride.
Pharmacological group: Antiallergic agent.
Pharmacological properties:
Telfast is an antihistamine drug that is an antagonist of histamine H-1 receptors. Does not sedate or otherwise affect the central nervous system. The antiallergic effect appears after 1 hour, after a maximum of 6 hours, continues to act for 24 hours.
Indications: elimination of symptoms associated with seasonal allergic rhinitis (SAR) or urticaria for adults and children over 12 years old.
Mode of application: SAR symptoms and urticaria: 180mg once daily before meals.
Patients at risk. Studies in special risk groups (elderly patients, with renal and hepatic insufficiency) have shown that no dosage adjustment is required for patients in these categories.
Contraindications: hypersensitivity to fexofenadine, terfenadine or other components of the drug.
Side effects: Fexofenadine is generally well tolerated. The most common (1-10% of cases) reported headache, fatigue, dizziness or drowsiness, and nausea. In placebo-controlled studies with a frequency of less than 1%, weakness, insomnia, nervousness, sleep disturbance, tachycardia, palpitations, and diarrhea were noted. In rare cases (less than 0.1%), exanthema, urticaria, itching, Quincke’s edema, shortness of breath, shortness of breath, reddening of the skin, anaphylactic reactions were observed.
Pregnancy Category B:
There are no adequate and well-controlled studies in pregnant women. Fexofenadine should be used during pregnancy only if the potential benefitjustifies the potential risk to the fetus.
Lactation: there are no data on the content of fexofenadine in breast milk when it is taken by breastfeeding women. Its penetration into breast milk was observed. The use of fexofenadine during breastfeeding is not recommended.
Precautions: Studies of elderly people, patients with hepatic impairment and patients with heart disease exposed to fexofenadine did not reveal statistically significant differences compared with healthy people. As with most new drugs, there is limited data on the elderly and patients with renal or hepatic insufficiency.
Fexofenadine hydrochloride should be used with caution in these special groups. Do not exceed the recommended dose of the drug. Do not drink fruit juices at the same time as fexofenadine: grapefruit, orange and apple can reduce its effectiveness.
Drug interactions: concomitant use with ketoconazole and erythromycin may increase the plasma concentration of fexofenadine. An antacid containing aluminum and magnesium can reduce the absorption of fexofenadine, the recommended interval between doses of these substances should be at least 2 hours.
Influence on the ability to drive a car and performance of work requiring concentration of attention: it is possible to perform work requiring a high concentration of attention and speed of psychomotor reactions (with the exception of patients with non-standard reactions). Therefore, it is recommended to check the individual reaction to taking fexofenadine before engaging in such activities.
Storage: Store at room temperature out of reach of children.
Packaging: a cardboard box contains 2 blisters, each containing 10 tablets and paper instructions.
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