Zovirax - 400 mg 10 Tablets

Treatment of infections of the skin and mucous membranes caused by herpes simplex virus types 1 and 2, including primary and recurrent genital herpes

prevention of recurrence of infections caused by the herpes simplex virus types 1 and 2 in patients with normal immune status prevention of infections caused by the herpes simplex virus types 1 and 2 in patients with immunodeficiency

treatment of primary and recurrent infections caused by the

Varicella zoster virus — chickenpox and herpes zoster (early treatment of herpes zoster with acyclovir has an analgesic effect and may reduce the incidence of postherpetic neuralgia)

Tradename: Zovirax

Zovirax

Composition: Each tablet contains:

Acyclovir — 400mg

Auxiliary components: microcrystalline cellulose, starch sodium gluconate, povidone 1<30, magnesium stearate, purified water.

Properties: Acyclovir is an antiviral agent. It has an effect on the Herpes simplex virus (types 1 and 2), the Varicella zoster virus.

Indications: treatment of infections of the skin and mucous membranes caused by Herpes simplex virus types 1 and 2, including primary and recurrent genital herpes; prevention of recurrence of infections caused by the herpes simplex vir types 1 and 2 in patients with normal immune

status; prevention of infections caused by the herpes simplex virus types 1 and 2 in patients with immunodeficiency; treatment of primary and recurrent infections caused by the

Varicella zoster virus — chickenpox and herpes zoster (early treatment of herpes zoster with acyclovir has an analgesic effect and may reduce the incidence of postherpetic neuralgia).

Mode of application: tablets can be dissolved in at least 50 ml of water or swallowed whole with a little water. Adults for herpes simplex infection: Take 200 mg 5 times a day every 4 hours, excluding nightly doses. The duration of treatment is 5 days, but in case of severe infections, it can be extended. For immunocompromised patients, the dose is 400 mg. Treatment should be started as early as possible when lesions first appear. Suppression of herpes simplex infections in immunocompromised patients: 200 mg 4 times daily at 6 hour intervals. Many patients are prescribed a regimen of 400 mg 2 times a day at 12 hour intervals. Dosages up to 200 mg, 3 times daily at 8 hour intervals, or even 2 times daily at approximately 12 hou apart, may be effective. Therapy should be interrupted periodically at intervals of 6 to 12 months, to observe possible changes in the disease. Prevention of herpes simplex infections with weakened immunity: 200 mg 4 times a day at approximately 6-hour intervals. In severely immunocompromised patients, the dose may be doubled to 400 mg. Treatment of chickenpox and herpes simplex: 800 mg 5 times a day at 4-hour intervals, skipping the nightly dose. Duration — 7 days. Treatment for chickenpox in immunocompetent patients should be initiated within 24 hours of the onset of the rash. Children for the treatment of herpes simplex infections and the prevention of herpes simplex syndrome with weakened immunity: from 2 years of age and older should be given doses for adults, and children under 2 years of age — half the dose for adults.

Treatment of chickenpox infection 6 years and older: 800 mg 4 times daily; 2-5 years: 400 mg 4 times a day; Under 2 years of age: 200 mg 4 times a day. The duration of treatment is 5 days. For patients with severe renal impairment, it is recommended to adjust the dose to 200 mg 2 times a day with an interval of 12 hours. In the treatment of herpes zoster, it is recommended to adjust the dosage to 800 mg 2 times a day with an interval of 12 hou For patients with severe renal impairment 800 mg 3 times a day with an interval of 8 hours for patients with moderate renal impairment.

Contraindications: hypersensitivity to acyclovir, valacyclovir or any of the other components in the composition, pregnancy and lactation.

Precautions: a lower dose is recommended for patients with impaired renal function, which is especially common in elderly patients. In case of impaired renal function, the doctor will adjust the dosage. When using acyclovir, it is necessary to monitor renal function (determination of the level of urea nitrogen in the blood and creatinine in the blood plasma). Drink plenty of fluids while taking acyclovir. When treating genital herpes, avoid intercourse or use condoms. the use of acyclovir does not prevent transmission of the virus to partners.

Side effects: the skin rash disappears when the drug is stopped. Nausea, vomiting, diarrhea, abdominal pain, headache, insomnia, fatigu dizziness, confusion, hallucinations, and drowsiness have been observed in patients with impaired renal function or other conditions. Hepatitis, jaundice, renal colic.

Storage: Store at a temperature not exceeding 30C in a dry, dark place and out of reach of children.

Packaging: a cardboard box contains 10 tablets, paper instructions.