Zyrtec - Syrup 100 ml

Antiallergic drug.

Trade name: Zyrtec

Composition: Each ml of solution contains:

Cetirizine dihydrochloride 1 mg

Auxiliary components:

Glycerol, propylene glycol, sodium saccharinate, methyl parabenzene, propyl parabenzene, sodium acetate, glacial acetic acid, purified water.

Properties: Antiallergic drug. A blocker of histamine H1 receptors, a competitive antagonist of histamine, a metabolite of hydroxyzine. Prevents the development and facilitates the course of allergic reactions, has an antipruritic and antiexudative effect.

Affects the early histamine-dependent stage of allergic reactions, limits the release of inflammatory mediators at the late stage of an allergic reaction, reduces the migration of eosinophils, neutrophils and basophils, stabilizes the membranes of mast cells. Reduces capillary permeability, prevents the development of tissue edema, relieves smooth muscle spasm. Eliminates skin reactions to the introduction of histamine, specific allergens, as well as to cooling (with «cold» urticaria). Reduces histamine-induced bronchoconstriction in mild bronchial asthma.

Virtually no anticholinergic and antiserotonin action. In therapeutic doses, it practically does not have a sedative effect.

After a single dose of cetirizine at a dose of 10 mg, the onset of the effect is observed after 20 minutes (in 50% of patients) and after 60 minutes (in 95% of patients), the effect lasts more than 24 hours. During the course of treatment, tolerance to the antihistamine effect of cetirizine does not develop. After stopping treatment, the effect persists for up to 3 days.

Indications: — treatment of symptoms of perennial and seasonal allergic rhinitis and allergic conjunctivitis, such as itching, sneezing, rhinorrhea, lacrimation, conjunctival hyperemia;

hay fever (hay fever);

— urticaria (including chronic idiopathic urticaria);

— Quincke’s edema;

— other allergic dermatoses (including atopic dermatitis), accompanied by itching and rashes.

Method of administration and dosage: The drug is administered orally.

Adults and children over 6 years of age are prescribed at a dose of 10 mg (1 tab. Or 10 ml of suspension) / day. Adults — 10 mg 1 time / day; children — 5 mg 2 times / day or 10 mg 1 time / day. Sometimes an initial dose of 5 mg may be sufficient to achieve a therapeutic effect.

Children aged 2 to 6 years are prescribed 2.5 mg (2.5 ml of suspension) 2 times / day or 5 mg (5 ml of suspension) 1 time / day.

Children aged 6 months to 12 months are prescribed the drug in drops of 2.5 mg (5 drops) 1 time / day.

Contraindications: — terminal stage of renal failure (CC <10 ml / min);

- pregnancy;

- period of lactation (breastfeeding)

— hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome;

- Children under 6 years old (for tablets);

- Children up to 6 months (for drops);

- increased sensitivity to the components of the drug;

- increased sensitivity to hydroxyzine.

Precautionary measures: For children aged 6 months to 6 years, Zyrtec is prescribed in a dosage form of drops for oral administration of 10 mg / ml.

Side effects:

From the hematopoietic system: thrombocytopenia.

From the nervous system: drowsiness, dizziness, headache, aggression, agitation, confusion, depression, hallucinations, insomnia, tics, convulsions, dyskinesia, dystonia, paresthesia, fainting, tremor.

From the side of the organ of vision: violation of accommodation, blurred vision, nystagmus.

On the part of the cardiovascular system: tachycardia.

From the respiratory system: rhinitis, pharyngitis.

From the digestive system: dry mouth, nausea, abdominal pain, diarrhea, liver dysfunction (increased levels of transaminases, alkaline phosphatase, GGT, bilirubin).

From the urinary system: urinary disorder, enuresis.

Allergic reactions: itching, rash, urticaria, angioedema, hypersensitivity, up to the development of anaphylactic shock.

Others: fatigue, asthenia, malaise, edema.

Side effects develop in very rare cases.

Storage method: Store at a temperature not exceeding 30 degrees.

Package: The cardboard box contains a 100 ml bottle and paper instructions.